Tag Index

2 items with this tag.

• Aug 18, 2026

  2026-06-28

  • gap/contradictory-evidence

• Aug 18, 2026

  2026-05-31

  • gap/dose-response-unclear
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap
  • gap/contradictory-evidence
  • gap/unsourced
  • gap/needs-fulltext-verification
  • gap/needs-pdf
  • gap/needs-healthy-population-replication

2 items with this tag.

• Aug 18, 2026

  R41

  • 3
  • gap/needs-full-text-verification
  • gap/needs-canonical-id

• Aug 18, 2026

  2026-06-04

  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/not-yet-done
  • gap/unsourced
  • gap/needs-replication
  • gap
  • gap/needs-canonical-id
  • 3

1 item with this tag.

• Aug 18, 2026

  2026-06-15

  • gap-tagged
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/contradictory-evidence
  • currentage

1000 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  white-adipose-tissue

  • gap/needs-page
  • gap/needs-human-replication
  • gap/no-mechanism

• Aug 18, 2026

  prostate

  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/long-term-unknown

• Aug 18, 2026

  skeletal-muscle

  • gap/unsourced
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  skin

  • gap/unsourced
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-fulltext-access

• Aug 18, 2026

  testis

  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  thymus

  • gap/no-fulltext-access
  • gap/no-mechanism

• Aug 18, 2026

  thyroid

  • gap/needs-replication
  • gap/unsourced
  • gap/contradictory-evidence

• Aug 18, 2026

  uterus

  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  vagus-nerve

  • gap/unsourced
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/no-mechanism

• Aug 18, 2026

  veins

  • gap/no-mechanism
  • gap/unsourced
  • gap/needs-replication

1 item with this tag.

• Aug 18, 2026

  2026-06-15

  • gap-tagged
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/contradictory-evidence
  • currentage

2 items with this tag.

• Aug 18, 2026

  A spatial multi-omics atlas of immunosenescence reveals germinal-center B cell alteration in human lymph nodes

  • gap/no-fulltext-access
  • gap/abstract-unavailable

• Aug 18, 2026

  2026-06-13

  • gap/no-fulltext-access
  • gap/future-seeding
  • gap/abstract-unavailable

1 item with this tag.

• Aug 18, 2026

  bacterial-cancer-therapy

  • gap/needs-primary-citation
  • gap/aging-context-untested
  • gap/no-mechanism
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • stub-needed

1 item with this tag.

• Aug 18, 2026

  intervention-classes

  • gap/class-normalisation-needed
  • gap/stub

1 item with this tag.

• Aug 18, 2026

  drometrizole-trisiloxane

  • gap/no-chembl-id
  • gap/comparative-spectral-data-needed
  • gap/no-independent-replication
  • gap/no-drt-isolated-efficacy-data
  • gap/no-biopsy-endpoint
  • gap/no-fda-pk-study
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/unverifiable-doi

430 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  thyroid

  • gap/needs-replication
  • gap/unsourced
  • gap/contradictory-evidence

• Aug 18, 2026

  vagus-nerve

  • gap/unsourced
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/no-mechanism

• Aug 18, 2026

  parathyroid

  • gap/unsourced
  • gap/dose-response-unclear
  • gap/contradictory-evidence
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  bone-marrow

  • gap/unsourced
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/needs-human-replication

• Aug 18, 2026

  bone

  • gap/unsourced
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-human-replication

• Aug 18, 2026

  brain

  • gap/unsourced
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism

• Aug 18, 2026

  breast

  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-fulltext-access

• Aug 18, 2026

  dermis

  • gap/unsourced
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-replication
  • gap/needs-human-replication

• Aug 18, 2026

  gingiva

  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/needs-verification

• Aug 18, 2026

  Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice

  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-human-replication

2 items with this tag.

• Aug 18, 2026

  R36

  • gap/unsourced
  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/cutoffs-not-from-primary-source

• Aug 18, 2026

  homa-ir-biomarker

  • gap/no-fulltext-access
  • gap/cutoffs-not-from-primary-source
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-replication

2 items with this tag.

• Aug 18, 2026

  elamipretide

  • gap/unsourced
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/unverified-archive-failure
  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/doi-unconfirmed
  • gap/long-term-unknown
  • stub
  • gap/no-fulltext-access

• Aug 18, 2026

  R34

  • gap/unsourced
  • gap/no-fulltext-access
  • gap/needs-canonical-id
  • gap/contradictory-evidence
  • gap/doi-unconfirmed
  • gap/needs-pdf-verification
  • gap/needs-replication

336 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  parathyroid

  • gap/unsourced
  • gap/dose-response-unclear
  • gap/contradictory-evidence
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  periodontal-ligament

  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-human-replication

• Aug 18, 2026

  Tobacco smoking and somatic mutations in human bronchial epithelium

  • gap/intercept-not-reported
  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-replication
  • gap/unsourced

• Aug 18, 2026

  Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice

  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-human-replication

• Aug 18, 2026

  Berberine ameliorates atherosclerosis by inhibiting the phenotypic transition of vascular smooth muscle cells via suppression of the JAK2/STAT3 signaling pathway

  • gap/needs-pdf-fetch
  • gap/needs-replication
  • gap/no-mechanism
  • gap/dose-response-unclear
  • gap/needs-human-replication

• Aug 18, 2026

  Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/long-term-unknown

• Aug 18, 2026

  Modulating IL-11-dependent matrix stiffness to delay ovarian aging

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/no-mechanism
  • gap/dose-response-unclear

• Aug 18, 2026

  Targeting senescent cells enhances adipogenesis and metabolic function in old age

  • gap/needs-human-replication
  • gap/dose-response-unclear

• Aug 18, 2026

  Efficacy and safety of berberine for several cardiovascular diseases: a systematic review and meta-analysis of randomized controlled trials

  • gap/no-fulltext-access
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/dose-response-unclear

• Aug 18, 2026

  Tretinoin (0.05% cream vs. 5% peel) for photoaging and field cancerization of the forearms: randomized, evaluator-blinded, clinical trial

  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/long-term-unknown

1 item with this tag.

• Aug 18, 2026

  2026-06-13

  • gap/no-fulltext-access
  • gap/future-seeding
  • gap/abstract-unavailable

1 item with this tag.

• Aug 18, 2026

  Discovery and characterization of antitumor gut microbiota from amphibians and reptiles: Ewingella americana as a novel therapeutic agent with dual cytotoxic and immunomodulatory properties

  • gap/needs-human-replication
  • gap/needs-supp-verification
  • gap/genome-not-sequenced
  • gap/no-mechanism
  • gap/needs-precedent-citation
  • gap/needs-replication

1 item with this tag.

• Aug 18, 2026

  low-back-pain

  • gap/unsourced
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/icd11-unverified
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  mendelian-randomization

  • gap/instrument-validity-uncertain

2 items with this tag.

• Aug 18, 2026

  Tobacco smoking and somatic mutations in human bronchial epithelium

  • gap/intercept-not-reported
  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-replication
  • gap/unsourced

• Aug 18, 2026

  2026-06-12

  • gaps
  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/loop-stability
  • gap/needs-state-node-migration
  • gap/intercept-not-reported

1 item with this tag.

• Aug 18, 2026

  obesity

  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/no-fulltext-access
  • gap/literature-checked-through-may-lag
  • gap/needs-human-replication
  • stub

411 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  prostate

  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/long-term-unknown

• Aug 18, 2026

  liver

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/unsourced
  • gap/long-term-unknown

• Aug 18, 2026

  ovary

  • gap/no-mechanism
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  parathyroid

  • gap/unsourced
  • gap/dose-response-unclear
  • gap/contradictory-evidence
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding

  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia

  • gap/long-term-unknown
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism

• Aug 18, 2026

  Gut-microbiota-targeted diets modulate human immune status

  • gap/needs-replication
  • gap/long-term-unknown

• Aug 18, 2026

  Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE™ trial

  • gap/needs-replication
  • gap/long-term-unknown

• Aug 18, 2026

  Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/long-term-unknown

• Aug 18, 2026

  Modulating IL-11-dependent matrix stiffness to delay ovarian aging

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/no-mechanism
  • gap/dose-response-unclear

1 item with this tag.

• Aug 18, 2026

  2026-06-12

  • gaps
  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/loop-stability
  • gap/needs-state-node-migration
  • gap/intercept-not-reported

1 item with this tag.

• Aug 18, 2026

  chronic-venous-disease

  • gap/dose-response-unclear
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/needs-human-replication
  • gap/needs-verification
  • gap/no-mechanism
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/low-evidence-source

1 item with this tag.

• Aug 18, 2026

  vsig4

  • gap/needs-genage-check
  • gap/no-mechanism
  • gap/needs-clinical-trials-recheck
  • gap/needs-gtex-age-stratified
  • gap/needs-sex-stratified-data
  • gap/mr-not-attempted
  • gap/needs-human-replication

1 item with this tag.

• Aug 18, 2026

  mediterranean-diet

  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/post-hoc-subgroup
  • gap/mrna-only-readout

2 items with this tag.

• Aug 18, 2026

  cancer

  • gap/unsourced
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/needs-aged-host-validation
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/long-term-unknown
  • gap/needs-full-extraction

• Aug 18, 2026

  nanoparticle-immunoadjuvants

  • gap/needs-human-replication
  • gap/needs-aged-host-validation
  • gap/long-term-unknown
  • gap/needs-mechanism
  • gap/dose-response-unclear
  • gap/needs-replication
  • gap/needs-full-extraction
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  aldh1a2

  • gap/no-fulltext-access
  • gap/needs-epigenetic-aging-citation
  • gap/no-opentargets-entry
  • gap/needs-human-replication
  • gap/needs-aging-expression-data
  • gap/needs-mouse-aging-expression
  • gap/dose-response-unclear

1 item with this tag.

• Aug 18, 2026

  heart-rate-zones

  • gap/needs-aging-specific-data
  • gap/contradictory-evidence
  • gap/needs-replication

1 item with this tag.

• Aug 18, 2026

  fpr2

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/needs-aging-trial
  • gap/contradictory-evidence
  • gap/needs-canonical-id
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  ghk-cu

  • gap/needs-canonical-id
  • gap/unsourced
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/needs-canonical-hallmark-assignment
  • gap/dose-response-unclear
  • gap/long-term-unknown

238 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  The skin aging exposome

  • gap/needs-canonical-id
  • gap/needs-replication
  • gap/unsourced
  • gap/long-term-unknown

• Aug 18, 2026

  The Epidermal Stem Cell Factor Is Over-Expressed in Lentigo Senilis: Implication for the Mechanism of Hyperpigmentation

  • gap/needs-replication
  • gap/needs-canonical-id
  • gap/contradictory-evidence
  • gap/no-mechanism

• Aug 18, 2026

  mtdna-heteroplasmy

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/unsourced
  • gap/dose-response-unclear
  • gap/needs-canonical-id

• Aug 18, 2026

  pentosidine

  • gap/needs-canonical-id
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/no-mechanism
  • gap/needs-human-replication

• Aug 18, 2026

  chaperone-mediated-autophagy

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • gap/long-term-unknown
  • gap/no-mechanism
  • gap/needs-canonical-id
  • gap/no-fulltext-access

• Aug 18, 2026

  dna-demethylation

  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/needs-canonical-id
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • gap/stub

• Aug 18, 2026

  glucosepane

  • gap/needs-canonical-id
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/needs-primary-source-verification
  • gap/dose-response-unclear

• Aug 18, 2026

  7-ketocholesterol

  • gap/no-fulltext-access
  • gap/needs-canonical-id
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/dose-response-unclear
  • gap/needs-replication

• Aug 18, 2026

  advanced-glycation-end-products

  • gap/needs-canonical-id
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap
  • gap/needs-primary-source-verification

• Aug 18, 2026

  rosacea

  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/stub
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/needs-canonical-id
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  Senolytic treatment rescues blunted muscle hypertrophy in old mice

  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/needs-canonical-ref-synergist-ablation

6 items with this tag.

• Aug 18, 2026

  il-1r1

  • gap/needs-replication
  • gap/needs-citation
  • gap/unsourced

• Aug 18, 2026

  hsp90

  • stub
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-citation
  • gap/long-term-unknown
  • gap/needs-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  growth-hormone-receptor

  • gap/needs-citation
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/stub
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/not-queried

• Aug 18, 2026

  navitoclax

  • gap/needs-canonical-id
  • gap/needs-human-replication
  • gap/unsourced
  • gap/no-fulltext-access
  • gap/needs-citation
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/no-mechanism
  • gap/dose-response-unclear

• Aug 18, 2026

  R35

  • gap/needs-citation
  • gap/needs-doi-confirmation
  • gap/no-fulltext-access
  • gap/unverified-source
  • gap/unsourced
  • gap/needs-replication
  • gap/stub
  • gap/dose-response-unclear

• Aug 18, 2026

  R25

  • gap/no-fulltext-access
  • gap/not-queried
  • gap/unsourced
  • gap/no-uniprot-noncoding-rna
  • gap/needs-citation
  • unsourced
  • gap/needs-replication
  • gap/needs-mechanistic-detail
  • gap/no-mechanism

1 item with this tag.

• Aug 18, 2026

  aromatase-inhibitors

  • gap/no-fulltext-access
  • gap/needs-citation-for-oophorectomy-bone-loss-comparison
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/long-term-unknown

1 item with this tag.

• Aug 18, 2026

  interventions-testing-program

  • gap/needs-citation-pass
  • gap/needs-replication
  • gap/needs-full-text
  • gap/needs-study-pages
  • gap/contradictory-evidence
  • gap/no-fulltext-access

4 items with this tag.

• Aug 18, 2026

  Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project

  • gap/needs-citation-verification
  • gap/long-term-unknown
  • gap/needs-nct-id-confirmation
  • stub
  • gap/no-disclosure

• Aug 18, 2026

  An open science study of ageing in companion dogs

  • gap/needs-replication
  • gap/long-term-unknown
  • gap/needs-citation-verification

• Aug 18, 2026

  canis-lupus-familiaris

  • gap/needs-replication
  • gap/needs-citation-verification
  • gap/no-disclosure
  • gap/contradictory-evidence
  • gap/no-fulltext-access

• Aug 18, 2026

  antagonistic-pleiotropy

  • gap/unsourced
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/no-mechanism
  • gap/needs-citation-verification

2 items with this tag.

• Aug 18, 2026

  vsig4

  • gap/needs-genage-check
  • gap/no-mechanism
  • gap/needs-clinical-trials-recheck
  • gap/needs-gtex-age-stratified
  • gap/needs-sex-stratified-data
  • gap/mr-not-attempted
  • gap/needs-human-replication

• Aug 18, 2026

  gpnmb

  • gap/needs-genage-check
  • gap/needs-human-replication
  • gap/no-aging-validated-probe
  • gap/needs-clinical-trials-recheck
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-gtex-age-stratified

1 item with this tag.

• Aug 18, 2026

  Age-dependent modulation of vascular niches for haematopoietic stem cells

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-corrigendum-review
  • gap/long-term-unknown
  • gap/dose-response-unclear

1 item with this tag.

• Aug 18, 2026

  berberine

  • gap/needs-ct-gov-count-refresh
  • gap/no-mechanism
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-verification
  • gap/long-term-unknown
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  dkk1

  • gap/needs-human-replication
  • gap/needs-current-trial-status
  • gap/dose-response-unclear
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  myd88

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-data

1 item with this tag.

• Aug 18, 2026

  R35

  • gap/needs-citation
  • gap/needs-doi-confirmation
  • gap/no-fulltext-access
  • gap/unverified-source
  • gap/unsourced
  • gap/needs-replication
  • gap/stub
  • gap/dose-response-unclear

1 item with this tag.

• Aug 18, 2026

  fgf23

  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-trials-check
  • gap/needs-druggability-check
  • stub
  • gap/needs-gtex-extraction
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  aldh1a2

  • gap/no-fulltext-access
  • gap/needs-epigenetic-aging-citation
  • gap/no-opentargets-entry
  • gap/needs-human-replication
  • gap/needs-aging-expression-data
  • gap/needs-mouse-aging-expression
  • gap/dose-response-unclear

2 items with this tag.

• Aug 18, 2026

  nrep

  • gap/needs-genage-check
  • gap/needs-human-replication
  • gap/needs-extended-data-verification
  • gap/no-druggable-probe
  • gap/no-mechanism
  • gap/needs-gtex-age-stratified
  • gap/contradictory-evidence
  • gap/no-fulltext-access

• Aug 18, 2026

  2026-05-29

  • gap/needs-human-replication
  • gap
  • gap/no-fulltext-access
  • gap/needs-extended-data-verification
  • gap/contradictory-evidence
  • gap/no-mechanism

1 item with this tag.

• Aug 18, 2026

  probiotics

  • gap/needs-human-replication
  • gap/no-approved-hydrogenotrophic-probiotic
  • gap/needs-extraction
  • gap/needs-invitro-gas-data
  • gap/no-direct-evidence
  • gap/contradictory-evidence
  • gap/needs-updated-survey
  • gap/needs-verification

4 items with this tag.

• Aug 18, 2026

  cancer

  • gap/unsourced
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/needs-aged-host-validation
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/long-term-unknown
  • gap/needs-full-extraction

• Aug 18, 2026

  type-i-interferon-signaling

  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • gap/no-fulltext-access
  • gap/needs-full-extraction

• Aug 18, 2026

  2026-05-21

  • gap/needs-supp-verification
  • gap/needs-full-extraction
  • gap/needs-replication
  • gap/needs-gtex-extraction
  • gap/unsourced

• Aug 18, 2026

  nanoparticle-immunoadjuvants

  • gap/needs-human-replication
  • gap/needs-aged-host-validation
  • gap/long-term-unknown
  • gap/needs-mechanism
  • gap/dose-response-unclear
  • gap/needs-replication
  • gap/needs-full-extraction
  • gap/no-fulltext-access

4 items with this tag.

• Aug 18, 2026

  RESULTS: FROM A RANDOMIZED CLINICAL TRIAL EVALUATING THE SENOLYTIC FISETIN FOR TREATING KNEE OSTEOARTHRITIS

  • gap/needs-full-paper-publication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/dose-response-unclear
  • gap/needs-human-replication
  • stub

• Aug 18, 2026

  fisetin

  • gap/no-mechanism
  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/needs-full-paper-publication

• Aug 18, 2026

  2026-06-30

  • gap/no-fulltext-access
  • gap/needs-full-paper-publication
  • gap/needs-human-replication
  • gap/contradictory-evidence

• Aug 18, 2026

  senolytics

  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/preprint-not-peer-reviewed
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-full-paper-publication

1 item with this tag.

• Aug 18, 2026

  il-6

  • gap/needs-human-replication
  • gap/needs-gtex-aging-correlation
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/dose-response-unclear
  • gap/needs-full-pdf-verification

2 items with this tag.

• Aug 18, 2026

  testosterone

  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/long-term-unknown
  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/needs-full-text

• Aug 18, 2026

  interventions-testing-program

  • gap/needs-citation-pass
  • gap/needs-replication
  • gap/needs-full-text
  • gap/needs-study-pages
  • gap/contradictory-evidence
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  R41

  • 3
  • gap/needs-full-text-verification
  • gap/needs-canonical-id

6 items with this tag.

• Aug 18, 2026

  Beneficial effects of vitamins D and K on the elastic properties of the vessel wall in postmenopausal women: a follow-up study

  • gap/no-fulltext-access
  • gap/needs-fulltext
  • gap/needs-replication
  • gap/dose-response-unclear

• Aug 18, 2026

  R44

  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/needs-fulltext

• Aug 18, 2026

  2026-06-09

  • gap/needs-canonical-id
  • gap/no-mechanism
  • gap/needs-fulltext
  • gap/no-fulltext-access

• Aug 18, 2026

  microneedling

  • gap/needs-fulltext
  • gap/needs-replication
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/contradictory-evidence
  • gap/dose-response-unclear

• Aug 18, 2026

  exosome-skin-therapy

  • gap/needs-mechanism
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/needs-fulltext

• Aug 18, 2026

  dermatologic-resurfacing

  • gap/needs-replication
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/dose-response-unclear
  • gap/long-term-unknown
  • gap/needs-fulltext

6 items with this tag.

• Aug 18, 2026

  p16INK4A is a robust in vivo biomarker of cellular aging in human skin

  • gap/no-fulltext-access
  • gap/needs-fulltext-verification
  • gap/no-mechanism
  • gap/contradictory-evidence

• Aug 18, 2026

  senescence-immune-surveillance

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/no-fulltext-access
  • gap/needs-fulltext-verification

• Aug 18, 2026

  immunosenescence

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/needs-fulltext-verification

• Aug 18, 2026

  romosozumab

  • gap/needs-canonical-id
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/needs-fulltext-verification

• Aug 18, 2026

  2026-05-31

  • gap/dose-response-unclear
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap
  • gap/contradictory-evidence
  • gap/unsourced
  • gap/needs-fulltext-verification
  • gap/needs-pdf
  • gap/needs-healthy-population-replication

• Aug 18, 2026

  disabled-adaptive-immunity

  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/needs-fulltext-verification

3 items with this tag.

• Aug 18, 2026

  vsig4

  • gap/needs-genage-check
  • gap/no-mechanism
  • gap/needs-clinical-trials-recheck
  • gap/needs-gtex-age-stratified
  • gap/needs-sex-stratified-data
  • gap/mr-not-attempted
  • gap/needs-human-replication

• Aug 18, 2026

  nrep

  • gap/needs-genage-check
  • gap/needs-human-replication
  • gap/needs-extended-data-verification
  • gap/no-druggable-probe
  • gap/no-mechanism
  • gap/needs-gtex-age-stratified
  • gap/contradictory-evidence
  • gap/no-fulltext-access

• Aug 18, 2026

  gpnmb

  • gap/needs-genage-check
  • gap/needs-human-replication
  • gap/no-aging-validated-probe
  • gap/needs-clinical-trials-recheck
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-gtex-age-stratified

4 items with this tag.

• Aug 18, 2026

  vsig4

  • gap/needs-genage-check
  • gap/no-mechanism
  • gap/needs-clinical-trials-recheck
  • gap/needs-gtex-age-stratified
  • gap/needs-sex-stratified-data
  • gap/mr-not-attempted
  • gap/needs-human-replication

• Aug 18, 2026

  sparc

  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-gtex-age-stratified
  • gap/contradictory-evidence

• Aug 18, 2026

  nrep

  • gap/needs-genage-check
  • gap/needs-human-replication
  • gap/needs-extended-data-verification
  • gap/no-druggable-probe
  • gap/no-mechanism
  • gap/needs-gtex-age-stratified
  • gap/contradictory-evidence
  • gap/no-fulltext-access

• Aug 18, 2026

  gpnmb

  • gap/needs-genage-check
  • gap/needs-human-replication
  • gap/no-aging-validated-probe
  • gap/needs-clinical-trials-recheck
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-gtex-age-stratified

9 items with this tag.

• Aug 18, 2026

  vkorc1

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/needs-gtex-aging-correlation
  • gap/no-mechanism

• Aug 18, 2026

  stat3

  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/needs-human-replication
  • gap/needs-gtex-aging-correlation

• Aug 18, 2026

  matrix-gla-protein

  • gap/unsourced
  • gap/needs-longitudinal-aging-trajectory
  • gap/contradictory-evidence
  • gap/needs-gtex-aging-correlation
  • gap/needs-human-replication

• Aug 18, 2026

  il-11-receptor-alpha-1

  • gap/long-term-unknown
  • gap/needs-human-replication
  • gap/needs-gtex-aging-correlation

• Aug 18, 2026

  il-11

  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/needs-gtex-aging-correlation

• Aug 18, 2026

  il-6

  • gap/needs-human-replication
  • gap/needs-gtex-aging-correlation
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/dose-response-unclear
  • gap/needs-full-pdf-verification

• Aug 18, 2026

  gp130

  • gap/needs-gtex-aging-correlation

• Aug 18, 2026

  ggcx

  • gap/needs-gtex-aging-correlation
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  bdnf

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-gtex-aging-correlation
  • gap/dose-response-unclear
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  camp

  • gap/needs-canonical-id
  • gap/needs-gtex-aging-data
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/no-mechanism

2 items with this tag.

• Aug 18, 2026

  il-1a

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-gtex-data
  • gap/needs-canonical-id
  • gap/no-fulltext-access

• Aug 18, 2026

  brca2

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/unsourced
  • gap/no-fulltext-access
  • gap
  • gap/needs-gtex-data

2 items with this tag.

• Aug 18, 2026

  fgf23

  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-trials-check
  • gap/needs-druggability-check
  • stub
  • gap/needs-gtex-extraction
  • gap/no-fulltext-access

• Aug 18, 2026

  2026-05-21

  • gap/needs-supp-verification
  • gap/needs-full-extraction
  • gap/needs-replication
  • gap/needs-gtex-extraction
  • gap/unsourced

2 items with this tag.

• Aug 18, 2026

  lrp5-lrp6

  • gap/no-mechanism
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/needs-gtex-lookup
  • gap/needs-canonical-id
  • gap/needs-mouse-ortholog

• Aug 18, 2026

  irak4

  • gap/unsourced
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/needs-gtex-lookup

1 item with this tag.

• Aug 18, 2026

  eda2r

  • gap/no-fulltext-access
  • gap/no-aging-probe
  • gap/no-mechanism
  • gap/needs-population-evidence
  • gap/needs-gtex-quantification
  • gap/unsourced
  • gap/needs-replication

3 items with this tag.

• Aug 18, 2026

  mc5r

  • gap/no-fulltext-access
  • gap/unsourced
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-gtex-query
  • gap/dose-response-unclear

• Aug 18, 2026

  irf3

  • gap/needs-canonical-id
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/needs-mechanism-clarity
  • gap/needs-gtex-query
  • gap/needs-replication

• Aug 18, 2026

  fancd2

  • gap/needs-canonical-id
  • gap/needs-verification
  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/no-mechanism
  • gap/needs-replication
  • stub
  • gap/long-term-unknown
  • gap/needs-gtex-query

1 item with this tag.

• Aug 18, 2026

  mc3r

  • gap/needs-gtex-subregion-data
  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/stub

1 item with this tag.

• Aug 18, 2026

  mexoryl-400

  • gap/no-independent-replication
  • gap/no-biopsy-endpoint
  • gap/needs-head-to-head-top-stack
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  bemotrizinol

  • gap/needs-replication
  • gap/needs-head-to-head-us-vs-eu-stack
  • gap/no-biopsy-endpoint
  • gap/needs-canonical-id
  • gap/long-term-unknown
  • gap/no-fulltext-access

3 items with this tag.

• Aug 18, 2026

  Semaglutide Slows Epigenetic Aging in People with HIV-associated lipohypertrophy: Evidence from a Randomized Controlled Trial

  • gap/needs-healthy-population-replication
  • gap/long-term-unknown

• Aug 18, 2026

  semaglutide

  • gap/needs-human-replication
  • gap/unsourced
  • gap/needs-healthy-population-replication
  • gap/no-mechanism
  • gap/needs-pdf-verification
  • gap/long-term-unknown
  • gap/dose-response-unclear

• Aug 18, 2026

  2026-05-31

  • gap/dose-response-unclear
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap
  • gap/contradictory-evidence
  • gap/unsourced
  • gap/needs-fulltext-verification
  • gap/needs-pdf
  • gap/needs-healthy-population-replication

730 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  white-adipose-tissue

  • gap/needs-page
  • gap/needs-human-replication
  • gap/no-mechanism

• Aug 18, 2026

  prostate

  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/long-term-unknown

• Aug 18, 2026

  skeletal-muscle

  • gap/unsourced
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  testis

  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  uterus

  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  vagus-nerve

  • gap/unsourced
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/no-mechanism

• Aug 18, 2026

  heart

  • gap/unsourced
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  lens

  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-replication

• Aug 18, 2026

  liver

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/unsourced
  • gap/long-term-unknown

• Aug 18, 2026

  myocardium

  • gap/unsourced
  • gap/needs-replication
  • gap/needs-human-replication

1 item with this tag.

• Aug 18, 2026

  gingival-recession

  • gap/needs-icd11-code
  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-quantitative-recession-rootcaries-risk
  • gap/no-fulltext-access
  • gap/dose-response-unclear
  • gap/needs-human-replication

1 item with this tag.

• Aug 18, 2026

  probiotics

  • gap/needs-human-replication
  • gap/no-approved-hydrogenotrophic-probiotic
  • gap/needs-extraction
  • gap/needs-invitro-gas-data
  • gap/no-direct-evidence
  • gap/contradictory-evidence
  • gap/needs-updated-survey
  • gap/needs-verification

1 item with this tag.

• Aug 18, 2026

  cd44

  • gap/needs-isoform-resolution
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/needs-replication

1 item with this tag.

• Aug 18, 2026

  matrix-gla-protein

  • gap/unsourced
  • gap/needs-longitudinal-aging-trajectory
  • gap/contradictory-evidence
  • gap/needs-gtex-aging-correlation
  • gap/needs-human-replication

3 items with this tag.

• Aug 18, 2026

  osteoarthritis

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/needs-mechanism
  • gap/no-mechanism
  • gap/contradictory-evidence

• Aug 18, 2026

  nanoparticle-immunoadjuvants

  • gap/needs-human-replication
  • gap/needs-aged-host-validation
  • gap/long-term-unknown
  • gap/needs-mechanism
  • gap/dose-response-unclear
  • gap/needs-replication
  • gap/needs-full-extraction
  • gap/no-fulltext-access

• Aug 18, 2026

  exosome-skin-therapy

  • gap/needs-mechanism
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/needs-fulltext

2 items with this tag.

• Aug 18, 2026

  mrn-complex

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-fulltext-access
  • gap/needs-mechanism-clarity
  • gap/unsourced

• Aug 18, 2026

  irf3

  • gap/needs-canonical-id
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/needs-mechanism-clarity
  • gap/needs-gtex-query
  • gap/needs-replication

2 items with this tag.

• Aug 18, 2026

  fgf21

  • gap/needs-canonical-id
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/needs-mechanistic-detail
  • gap/no-human-aging-trial
  • gap/long-term-unknown

• Aug 18, 2026

  R25

  • gap/no-fulltext-access
  • gap/not-queried
  • gap/unsourced
  • gap/no-uniprot-noncoding-rna
  • gap/needs-citation
  • unsourced
  • gap/needs-replication
  • gap/needs-mechanistic-detail
  • gap/no-mechanism

1 item with this tag.

• Aug 18, 2026

  aldh1a2

  • gap/no-fulltext-access
  • gap/needs-epigenetic-aging-citation
  • gap/no-opentargets-entry
  • gap/needs-human-replication
  • gap/needs-aging-expression-data
  • gap/needs-mouse-aging-expression
  • gap/dose-response-unclear

1 item with this tag.

• Aug 18, 2026

  lrp5-lrp6

  • gap/no-mechanism
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/needs-gtex-lookup
  • gap/needs-canonical-id
  • gap/needs-mouse-ortholog

1 item with this tag.

• Aug 18, 2026

  Astaxanthin, meclizine, mitoglitazone, pioglitazone, alpha-ketoglutarate, mifepristone, methotrexate, and atorvastatin-telmisartan do not increase lifespan in UM-HET3 mice

  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/needs-n-confirmation
  • gap/no-mechanism
  • gap/dose-response-unclear

1 item with this tag.

• Aug 18, 2026

  Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project

  • gap/needs-citation-verification
  • gap/long-term-unknown
  • gap/needs-nct-id-confirmation
  • stub
  • gap/no-disclosure

4 items with this tag.

• Aug 18, 2026

  white-adipose-tissue

  • gap/needs-page
  • gap/needs-human-replication
  • gap/no-mechanism

• Aug 18, 2026

  Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

  • gap/needs-human-replication
  • gap/needs-page

• Aug 18, 2026

  2026-05-23

  • gap/no-fulltext-access
  • gap/no-mechanism
  • gap
  • gap/needs-page
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/needs-replication

• Aug 18, 2026

  osteoclasts

  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/needs-sc-aging-data
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-replication
  • gap/needs-page

1 item with this tag.

• Aug 18, 2026

  2026-05-31

  • gap/dose-response-unclear
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap
  • gap/contradictory-evidence
  • gap/unsourced
  • gap/needs-fulltext-verification
  • gap/needs-pdf
  • gap/needs-healthy-population-replication

1 item with this tag.

• Aug 18, 2026

  Berberine ameliorates atherosclerosis by inhibiting the phenotypic transition of vascular smooth muscle cells via suppression of the JAK2/STAT3 signaling pathway

  • gap/needs-pdf-fetch
  • gap/needs-replication
  • gap/no-mechanism
  • gap/dose-response-unclear
  • gap/needs-human-replication

10 items with this tag.

• Aug 18, 2026

  epidermis

  • gap/unsourced
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/needs-pdf-verification

• Aug 18, 2026

  Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes

  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/needs-pdf-verification
  • gap/no-mechanism
  • gap/needs-replication

• Aug 18, 2026

  Semaglutide ameliorates osteoarthritis progression through a weight loss-independent metabolic restoration mechanism

  • gap/needs-pdf-verification
  • gap/needs-replication

• Aug 18, 2026

  skin-aging

  • gap/needs-human-replication
  • gap/unsourced
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/long-term-unknown
  • gap/dose-response-unclear
  • gap/needs-pdf-verification

• Aug 18, 2026

  sw033291

  • gap/needs-canonical-id
  • gap/needs-pdf-verification
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • gap/long-term-unknown
  • gap/unsourced

• Aug 18, 2026

  semaglutide

  • gap/needs-human-replication
  • gap/unsourced
  • gap/needs-healthy-population-replication
  • gap/no-mechanism
  • gap/needs-pdf-verification
  • gap/long-term-unknown
  • gap/dose-response-unclear

• Aug 18, 2026

  R34

  • gap/unsourced
  • gap/no-fulltext-access
  • gap/needs-canonical-id
  • gap/contradictory-evidence
  • gap/doi-unconfirmed
  • gap/needs-pdf-verification
  • gap/needs-replication

• Aug 18, 2026

  log

  • gap/dose-response-unclear
  • gap/unsourced
  • gap/no-fulltext-access
  • gap/needs-canonical-id
  • gap/needs-pdf-verification

• Aug 18, 2026

  glp1-agonists

  • gap/no-mechanism
  • gap/unsourced
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/needs-pdf-verification
  • gap/contradictory-evidence
  • gap/dose-response-unclear
  • gap/long-term-unknown

• Aug 18, 2026

  qi-23k-epidermis-clock-2026

  • gap/needs-pdf-verification
  • gap/needs-replication
  • gap/no-mechanism

8 items with this tag.

• Aug 18, 2026

  The Immunoglobulin G Glycome: A Modifiable Biomarker and Functional Effector of Aging, Disease, and Mortality

  • gap/needs-peer-review
  • gap/needs-replication

• Aug 18, 2026

  Ancestral protein reconstruction reveals the mechanism of substrate specificity in FN3K-mediated deglycation

  • gap/needs-peer-review
  • gap/needs-replication

• Aug 18, 2026

  fn3k

  • gap/needs-replication
  • gap/needs-peer-review
  • gap/no-mechanism

• Aug 18, 2026

  2026-05-20

  • gap/no-mechanism
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • gap/not-in-genage
  • gap/unsourced
  • gap/needs-canonical-id
  • gap/needs-peer-review

• Aug 18, 2026

  plasma-exchange

  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-peer-review
  • gap/unsourced
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/no-mechanism
  • gap/dose-response-unclear
  • gap/no-fulltext-access

• Aug 18, 2026

  chronic-inflammation

  • gap/no-mechanism
  • gap/unsourced
  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/needs-peer-review
  • gap/long-term-unknown
  • gap/no-fulltext-access-yet

• Aug 18, 2026

  biological-age-measurement

  • gap/needs-peer-review
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/contradictory-evidence

• Aug 18, 2026

  glycanage-2017

  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/needs-peer-review
  • gap/unsourced
  • gap/needs-canonical-id

1 item with this tag.

• Aug 18, 2026

  15-pgdh

  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/needs-pk-data
  • gap/proprietary-chemistry
  • gap/long-term-unknown
  • gap/contradictory-evidence
  • gap/dose-response-unclear
  • gap/needs-canonical-id

1 item with this tag.

• Aug 18, 2026

  tak1

  • gap/needs-replication
  • gap/no-mechanism
  • gap/unsourced
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/needs-population-data
  • gap/needs-canonical-id

2 items with this tag.

• Aug 18, 2026

  mc1r

  • gap/dose-response-unclear
  • gap/needs-population-evidence
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  eda2r

  • gap/no-fulltext-access
  • gap/no-aging-probe
  • gap/no-mechanism
  • gap/needs-population-evidence
  • gap/needs-gtex-quantification
  • gap/unsourced
  • gap/needs-replication

1 item with this tag.

• Aug 18, 2026

  Discovery and characterization of antitumor gut microbiota from amphibians and reptiles: Ewingella americana as a novel therapeutic agent with dual cytotoxic and immunomodulatory properties

  • gap/needs-human-replication
  • gap/needs-supp-verification
  • gap/genome-not-sequenced
  • gap/no-mechanism
  • gap/needs-precedent-citation
  • gap/needs-replication

1 item with this tag.

• Aug 18, 2026

  bacterial-cancer-therapy

  • gap/needs-primary-citation
  • gap/aging-context-untested
  • gap/no-mechanism
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • stub-needed

1 item with this tag.

• Aug 18, 2026

  noxa

  • gap/needs-canonical-id
  • gap/unsourced
  • gap/needs-primary-citation-for-human-p53re-coordinates
  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-replication

5 items with this tag.

• Aug 18, 2026

  atr

  • gap/needs-canonical-id
  • gap/needs-primary-source
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/unsourced
  • gap/needs-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  bad

  • gap/needs-canonical-id
  • gap/needs-primary-source
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/unsourced
  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/long-term-unknown

• Aug 18, 2026

  14-3-3

  • gap/needs-replication
  • gap/needs-primary-source
  • gap/unsourced
  • gap/long-term-unknown
  • gap/needs-canonical-id
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • gap/no-fulltext-access

• Aug 18, 2026

  R5

  • gap/unsourced
  • gap/no-mechanism
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/needs-canonical-id
  • gap
  • gap/needs-primary-source
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/dose-response-unclear

• Aug 18, 2026

  R31

  • gap/no-fulltext-access
  • gap/needs-primary-source
  • gap/needs-replication
  • gap/unsourced
  • gap/needs-canonical-id

4 items with this tag.

• Aug 18, 2026

  glucosepane

  • gap/needs-canonical-id
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/needs-primary-source-verification
  • gap/dose-response-unclear

• Aug 18, 2026

  advanced-glycation-end-products

  • gap/needs-canonical-id
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap
  • gap/needs-primary-source-verification

• Aug 18, 2026

  age-crosslink-breakers

  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/needs-primary-source-verification
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  sens-damage-categories

  • gap/needs-primary-source-verification
  • gap/contradictory-evidence

1 item with this tag.

• Aug 18, 2026

  gingival-recession

  • gap/needs-icd11-code
  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-quantitative-recession-rootcaries-risk
  • gap/no-fulltext-access
  • gap/dose-response-unclear
  • gap/needs-human-replication

1 item with this tag.

• Aug 18, 2026

  bpc-157

  • gap/needs-canonical-id
  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/needs-regulatory-update
  • gap/long-term-unknown

822 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  skin

  • gap/unsourced
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-fulltext-access

• Aug 18, 2026

  thyroid

  • gap/needs-replication
  • gap/unsourced
  • gap/contradictory-evidence

• Aug 18, 2026

  veins

  • gap/no-mechanism
  • gap/unsourced
  • gap/needs-replication

• Aug 18, 2026

  heart

  • gap/unsourced
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  lens

  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-replication

• Aug 18, 2026

  liver

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/unsourced
  • gap/long-term-unknown

• Aug 18, 2026

  myocardium

  • gap/unsourced
  • gap/needs-replication
  • gap/needs-human-replication

• Aug 18, 2026

  ovary

  • gap/no-mechanism
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  arteries

  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  bone-marrow

  • gap/unsourced
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/needs-human-replication

3 items with this tag.

• Aug 18, 2026

  osteoblasts

  • gap/no-fulltext-access
  • gap/dose-response-unclear
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/needs-sc-aging-data

• Aug 18, 2026

  osteoclasts

  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/needs-sc-aging-data
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-replication
  • gap/needs-page

• Aug 18, 2026

  osteocytes

  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-sc-aging-data
  • gap/no-fulltext-access
  • gap/needs-human-replication

1 item with this tag.

• Aug 18, 2026

  iscotrizinol

  • gap/needs-sccs-opinion-ref
  • gap/needs-human-replication
  • gap/no-isolated-compound-rct
  • gap/long-term-unknown
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  tinosorb-a2b

  • gap/needs-sccs-opinion-reference-confirmed
  • gap/no-human-rct
  • gap/no-independent-replication
  • gap/no-biopsy-endpoint
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/no-mechanism

1 item with this tag.

• Aug 18, 2026

  interventions-by-hallmark

  • gap/needs-seeding
  • gap/needs-tagging

1 item with this tag.

• Aug 18, 2026

  hyal2

  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/needs-selective-inhibitor
  • gap/needs-tissue-expression-check
  • gap/needs-replication

1 item with this tag.

• Aug 18, 2026

  alpha-tocopherol

  • gap/needs-replication
  • gap/needs-separate-page
  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • stub
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  Targeting iron-associated protein Ftl1 in the brain of old mice improves age-related cognitive impairment

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-sex-stratification
  • gap/dose-response-unclear
  • gap/long-term-unknown

1 item with this tag.

• Aug 18, 2026

  vsig4

  • gap/needs-genage-check
  • gap/no-mechanism
  • gap/needs-clinical-trials-recheck
  • gap/needs-gtex-age-stratified
  • gap/needs-sex-stratified-data
  • gap/mr-not-attempted
  • gap/needs-human-replication

1 item with this tag.

• Aug 18, 2026

  2026-06-12

  • gaps
  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/loop-stability
  • gap/needs-state-node-migration
  • gap/intercept-not-reported

1 item with this tag.

• Aug 18, 2026

  ewingella-americana

  • gap/needs-replication
  • gap/needs-strain-genome
  • gap/unsourced
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • gap/long-term-unknown
  • gap/no-mechanism
  • gap/no-fulltext-access

2 items with this tag.

• Aug 18, 2026

  chrna7

  • gap/needs-human-replication
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/long-term-unknown
  • gap/needs-stub
  • gap/no-mechanism
  • gap/not-queried

• Aug 18, 2026

  caspase-1

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/needs-stub
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

  • gap/needs-replication
  • gap/needs-stub-expansion

1 item with this tag.

• Aug 18, 2026

  interventions-testing-program

  • gap/needs-citation-pass
  • gap/needs-replication
  • gap/needs-full-text
  • gap/needs-study-pages
  • gap/contradictory-evidence
  • gap/no-fulltext-access

3 items with this tag.

• Aug 18, 2026

  Lanosterol reverses protein aggregation in cataracts

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/needs-supp-verification
  • gap/contradictory-evidence

• Aug 18, 2026

  Discovery and characterization of antitumor gut microbiota from amphibians and reptiles: Ewingella americana as a novel therapeutic agent with dual cytotoxic and immunomodulatory properties

  • gap/needs-human-replication
  • gap/needs-supp-verification
  • gap/genome-not-sequenced
  • gap/no-mechanism
  • gap/needs-precedent-citation
  • gap/needs-replication

• Aug 18, 2026

  2026-05-21

  • gap/needs-supp-verification
  • gap/needs-full-extraction
  • gap/needs-replication
  • gap/needs-gtex-extraction
  • gap/unsourced

2 items with this tag.

• Aug 18, 2026

  R45

  • gap
  • gap/needs-tagging

• Aug 18, 2026

  interventions-by-hallmark

  • gap/needs-seeding
  • gap/needs-tagging

1 item with this tag.

• Aug 18, 2026

  hyal2

  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/needs-selective-inhibitor
  • gap/needs-tissue-expression-check
  • gap/needs-replication

9 items with this tag.

• Aug 18, 2026

  spry1

  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/no-opentargets-entry
  • gap/long-term-unknown
  • gap/needs-human-replication
  • gap/needs-tissue-expression-data

• Aug 18, 2026

  pomc

  • gap/needs-canonical-id
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-replication
  • stub
  • gap/needs-tissue-expression-data
  • gap/contradictory-evidence
  • gap/no-fulltext-access

• Aug 18, 2026

  nefl

  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/needs-tissue-expression-data
  • gap/no-mechanism
  • gap/not-tested-mr
  • gap/needs-canonical-id

• Aug 18, 2026

  mc4r

  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/unsourced
  • gap/no-mechanism
  • gap/needs-tissue-expression-data

• Aug 18, 2026

  inhba

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/dose-response-unclear
  • gap/contradictory-evidence
  • gap/needs-tissue-expression-data
  • gap/no-fulltext-access

• Aug 18, 2026

  fgf2

  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/no-opentargets-entry
  • gap/needs-replication
  • gap/needs-tissue-expression-data
  • gap/contradictory-evidence
  • gap/no-fulltext-access

• Aug 18, 2026

  fgfr1

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-tissue-expression-data
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  crh

  • gap/needs-canonical-id
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/needs-tissue-expression-data
  • gap/no-fulltext-access

• Aug 18, 2026

  alpha-msh

  • gap/needs-human-replication
  • gap/needs-canonical-id
  • gap/needs-tissue-expression-data
  • gap/long-term-unknown
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  fgf23

  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/needs-trials-check
  • gap/needs-druggability-check
  • stub
  • gap/needs-gtex-extraction
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  polycystic-ovary-syndrome

  • gap/contradictory-evidence
  • gap/needs-updated-citation
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-data
  • gap/needs-canonical-id
  • gap/wrong-doi

1 item with this tag.

• Aug 18, 2026

  probiotics

  • gap/needs-human-replication
  • gap/no-approved-hydrogenotrophic-probiotic
  • gap/needs-extraction
  • gap/needs-invitro-gas-data
  • gap/no-direct-evidence
  • gap/contradictory-evidence
  • gap/needs-updated-survey
  • gap/needs-verification

20 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  gingiva

  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/needs-verification

• Aug 18, 2026

  A damage accumulation model identifies distinct aging regimes across species

  • gap/needs-verification

• Aug 18, 2026

  Regeneration of neuromuscular synapses after acute and chronic denervation by inhibiting the gerozyme 15-prostaglandin dehydrogenase

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-verification
  • gap/long-term-unknown
  • gap/dose-response-unclear

• Aug 18, 2026

  menopause

  • gap/no-fulltext-access
  • gap/needs-verification
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/unsourced
  • stub

• Aug 18, 2026

  genitourinary-syndrome-menopause

  • gap/needs-verification
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/contradictory-evidence

• Aug 18, 2026

  chronic-venous-disease

  • gap/dose-response-unclear
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/needs-human-replication
  • gap/needs-verification
  • gap/no-mechanism
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/low-evidence-source

• Aug 18, 2026

  andropause

  • gap/needs-verification
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/long-term-unknown

• Aug 18, 2026

  nlrp3-inflammasome

  • gap/needs-human-replication
  • gap/unsourced
  • gap/no-mechanism
  • gap/dose-response-unclear
  • gap/long-term-unknown
  • gap/needs-replication
  • gap/needs-verification

• Aug 18, 2026

  lgals3

  • gap/needs-canonical-id
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/needs-verification
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/needs-human-replication

• Aug 18, 2026

  has2

  • gap/needs-canonical-id
  • gap/needs-verification
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/unsourced
  • gap/no-mechanism
  • gap/dose-response-unclear
  • gap/needs-replication

1 item with this tag.

• Aug 18, 2026

  eda2r

  • gap/no-fulltext-access
  • gap/no-aging-probe
  • gap/no-mechanism
  • gap/needs-population-evidence
  • gap/needs-gtex-quantification
  • gap/unsourced
  • gap/needs-replication

1 item with this tag.

• Aug 18, 2026

  gpnmb

  • gap/needs-genage-check
  • gap/needs-human-replication
  • gap/no-aging-validated-probe
  • gap/needs-clinical-trials-recheck
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/needs-gtex-age-stratified

1 item with this tag.

• Aug 18, 2026

  probiotics

  • gap/needs-human-replication
  • gap/no-approved-hydrogenotrophic-probiotic
  • gap/needs-extraction
  • gap/needs-invitro-gas-data
  • gap/no-direct-evidence
  • gap/contradictory-evidence
  • gap/needs-updated-survey
  • gap/needs-verification

6 items with this tag.

• Aug 18, 2026

  tinosorb-a2b

  • gap/needs-sccs-opinion-reference-confirmed
  • gap/no-human-rct
  • gap/no-independent-replication
  • gap/no-biopsy-endpoint
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/no-mechanism

• Aug 18, 2026

  mexoryl-400

  • gap/no-independent-replication
  • gap/no-biopsy-endpoint
  • gap/needs-head-to-head-top-stack
  • gap/no-fulltext-access

• Aug 18, 2026

  drometrizole-trisiloxane

  • gap/no-chembl-id
  • gap/comparative-spectral-data-needed
  • gap/no-independent-replication
  • gap/no-drt-isolated-efficacy-data
  • gap/no-biopsy-endpoint
  • gap/no-fda-pk-study
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/unverifiable-doi

• Aug 18, 2026

  ecamsule

  • gap/no-independent-replication
  • gap/no-biopsy-endpoint
  • gap/long-term-unknown
  • gap/regulatory-gap
  • gap/no-fulltext-access

• Aug 18, 2026

  bemotrizinol

  • gap/needs-replication
  • gap/needs-head-to-head-us-vs-eu-stack
  • gap/no-biopsy-endpoint
  • gap/needs-canonical-id
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  bisoctrizole

  • gap/no-direct-comparator-rct
  • gap/no-biopsy-endpoint
  • gap/long-term-unknown
  • gap/needs-canonical-id
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  drometrizole-trisiloxane

  • gap/no-chembl-id
  • gap/comparative-spectral-data-needed
  • gap/no-independent-replication
  • gap/no-drt-isolated-efficacy-data
  • gap/no-biopsy-endpoint
  • gap/no-fda-pk-study
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/unverifiable-doi

1 item with this tag.

• Aug 18, 2026

  polycystic-ovary-syndrome

  • gap/contradictory-evidence
  • gap/needs-updated-citation
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-data
  • gap/needs-canonical-id
  • gap/wrong-doi

2 items with this tag.

• Aug 18, 2026

  triasorb

  • gap/no-independent-replication
  • gap/no-direct-comparator-rct
  • gap/long-term-unknown

• Aug 18, 2026

  bisoctrizole

  • gap/no-direct-comparator-rct
  • gap/no-biopsy-endpoint
  • gap/long-term-unknown
  • gap/needs-canonical-id
  • gap/no-fulltext-access

2 items with this tag.

• Aug 18, 2026

  probiotics

  • gap/needs-human-replication
  • gap/no-approved-hydrogenotrophic-probiotic
  • gap/needs-extraction
  • gap/needs-invitro-gas-data
  • gap/no-direct-evidence
  • gap/contradictory-evidence
  • gap/needs-updated-survey
  • gap/needs-verification

• Aug 18, 2026

  resistant-starch

  • gap/dose-response-unclear
  • gap/long-term-unknown
  • gap/no-direct-evidence

3 items with this tag.

• Aug 18, 2026

  Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project

  • gap/needs-citation-verification
  • gap/long-term-unknown
  • gap/needs-nct-id-confirmation
  • stub
  • gap/no-disclosure

• Aug 18, 2026

  canis-lupus-familiaris

  • gap/needs-replication
  • gap/needs-citation-verification
  • gap/no-disclosure
  • gap/contradictory-evidence
  • gap/no-fulltext-access

• Aug 18, 2026

  ppara-agonists

  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/unsourced
  • gap/no-disclosure
  • gap/no-mechanism
  • gap/no-fulltext-access
  • non-peer-reviewed-analysis

1 item with this tag.

• Aug 18, 2026

  drometrizole-trisiloxane

  • gap/no-chembl-id
  • gap/comparative-spectral-data-needed
  • gap/no-independent-replication
  • gap/no-drt-isolated-efficacy-data
  • gap/no-biopsy-endpoint
  • gap/no-fda-pk-study
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/unverifiable-doi

1 item with this tag.

• Aug 18, 2026

  nrep

  • gap/needs-genage-check
  • gap/needs-human-replication
  • gap/needs-extended-data-verification
  • gap/no-druggable-probe
  • gap/no-mechanism
  • gap/needs-gtex-age-stratified
  • gap/contradictory-evidence
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  drometrizole-trisiloxane

  • gap/no-chembl-id
  • gap/comparative-spectral-data-needed
  • gap/no-independent-replication
  • gap/no-drt-isolated-efficacy-data
  • gap/no-biopsy-endpoint
  • gap/no-fda-pk-study
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/unverifiable-doi

527 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  prostate

  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/long-term-unknown

• Aug 18, 2026

  skeletal-muscle

  • gap/unsourced
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  skin

  • gap/unsourced
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-fulltext-access

• Aug 18, 2026

  testis

  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  thymus

  • gap/no-fulltext-access
  • gap/no-mechanism

• Aug 18, 2026

  uterus

  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  heart

  • gap/unsourced
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  ovary

  • gap/no-mechanism
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  parathyroid

  • gap/unsourced
  • gap/dose-response-unclear
  • gap/contradictory-evidence
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  arteries

  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  chronic-inflammation

  • gap/no-mechanism
  • gap/unsourced
  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/needs-peer-review
  • gap/long-term-unknown
  • gap/no-fulltext-access-yet

1 item with this tag.

• Aug 18, 2026

  dna-pkcs

  • gap/no-genage-entry
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/long-term-unknown
  • gap/dose-response-unclear

1 item with this tag.

• Aug 18, 2026

  tmsb4x

  • gap/needs-canonical-id
  • gap/no-gtex-aging-signal
  • gap/dose-response-unclear
  • gap/needs-human-replication
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  fgf21

  • gap/needs-canonical-id
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/needs-mechanistic-detail
  • gap/no-human-aging-trial
  • gap/long-term-unknown

1 item with this tag.

• Aug 18, 2026

  tinosorb-a2b

  • gap/needs-sccs-opinion-reference-confirmed
  • gap/no-human-rct
  • gap/no-independent-replication
  • gap/no-biopsy-endpoint
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/no-mechanism

6 items with this tag.

• Aug 18, 2026

  tinosorb-a2b

  • gap/needs-sccs-opinion-reference-confirmed
  • gap/no-human-rct
  • gap/no-independent-replication
  • gap/no-biopsy-endpoint
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/no-mechanism

• Aug 18, 2026

  triasorb

  • gap/no-independent-replication
  • gap/no-direct-comparator-rct
  • gap/long-term-unknown

• Aug 18, 2026

  mexoryl-400

  • gap/no-independent-replication
  • gap/no-biopsy-endpoint
  • gap/needs-head-to-head-top-stack
  • gap/no-fulltext-access

• Aug 18, 2026

  drometrizole-trisiloxane

  • gap/no-chembl-id
  • gap/comparative-spectral-data-needed
  • gap/no-independent-replication
  • gap/no-drt-isolated-efficacy-data
  • gap/no-biopsy-endpoint
  • gap/no-fda-pk-study
  • gap/long-term-unknown
  • gap/no-fulltext-access
  • gap/unverifiable-doi

• Aug 18, 2026

  ecamsule

  • gap/no-independent-replication
  • gap/no-biopsy-endpoint
  • gap/long-term-unknown
  • gap/regulatory-gap
  • gap/no-fulltext-access

• Aug 18, 2026

  uv-protection

  • gap/needs-replication
  • gap/no-independent-replication
  • gap/long-term-unknown
  • gap/dose-response-unclear
  • gap/no-fulltext-access

1 item with this tag.

• Aug 18, 2026

  iscotrizinol

  • gap/needs-sccs-opinion-ref
  • gap/needs-human-replication
  • gap/no-isolated-compound-rct
  • gap/long-term-unknown
  • gap/no-fulltext-access

640 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  white-adipose-tissue

  • gap/needs-page
  • gap/needs-human-replication
  • gap/no-mechanism

• Aug 18, 2026

  skin

  • gap/unsourced
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-fulltext-access

• Aug 18, 2026

  thymus

  • gap/no-fulltext-access
  • gap/no-mechanism

• Aug 18, 2026

  vagus-nerve

  • gap/unsourced
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/no-mechanism

• Aug 18, 2026

  veins

  • gap/no-mechanism
  • gap/unsourced
  • gap/needs-replication

• Aug 18, 2026

  lens

  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/needs-replication

• Aug 18, 2026

  ovary

  • gap/no-mechanism
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  periodontal-ligament

  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-human-replication

• Aug 18, 2026

  arteries

  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  brain

  • gap/unsourced
  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism

1 item with this tag.

• Aug 18, 2026

  Using human genetics to understand the disease impacts of testosterone in men and women

  • gap/no-narrative-or-stated
  • gap/contradictory-evidence

12 items with this tag. Showing first 10 tags.

• Aug 18, 2026

  spry1

  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/no-opentargets-entry
  • gap/long-term-unknown
  • gap/needs-human-replication
  • gap/needs-tissue-expression-data

• Aug 18, 2026

  sirt3

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/no-mechanism
  • gap/needs-canonical-id
  • gap/no-opentargets-entry

• Aug 18, 2026

  smad2-smad3

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/needs-canonical-id
  • gap/no-mechanism
  • gap/no-opentargets-entry

• Aug 18, 2026

  prox1

  • gap/needs-canonical-id
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/unsourced
  • gap/no-opentargets-entry
  • gap/no-mechanism

• Aug 18, 2026

  mutyh

  • gap/unsourced
  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/no-opentargets-entry

• Aug 18, 2026

  klotho

  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/contradictory-evidence
  • gap/dose-response-unclear
  • gap/no-opentargets-entry
  • stub

• Aug 18, 2026

  gpr43

  • gap/no-fulltext-access
  • gap/unsourced
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/no-opentargets-entry
  • gap/long-term-unknown
  • gap/dose-response-unclear

• Aug 18, 2026

  gdf11

  • gap/contradictory-evidence
  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/no-mechanism
  • gap/needs-replication
  • gap/no-opentargets-entry

• Aug 18, 2026

  fgf2

  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/no-opentargets-entry
  • gap/needs-replication
  • gap/needs-tissue-expression-data
  • gap/contradictory-evidence
  • gap/no-fulltext-access

• Aug 18, 2026

  aldh1a1

  • gap/needs-canonical-id
  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/no-mechanism
  • gap/unsourced
  • gap/no-opentargets-entry
  • stub

1 item with this tag.

• Aug 18, 2026

  ovarian-stromal-fibroblasts

  • gap/no-singlecell-data
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/long-term-unknown

2 items with this tag.

• Aug 18, 2026

  terc

  • gap/no-uniprot-noncoding-rna
  • gap/needs-replication
  • gap/long-term-unknown
  • gap/unsourced
  • gap/no-mechanism
  • gap/no-fulltext-access

• Aug 18, 2026

  R25

  • gap/no-fulltext-access
  • gap/not-queried
  • gap/unsourced
  • gap/no-uniprot-noncoding-rna
  • gap/needs-citation
  • unsourced
  • gap/needs-replication
  • gap/needs-mechanistic-detail
  • gap/no-mechanism

1 item with this tag.

• Aug 18, 2026

  mlh1

  • gap/no-mechanism
  • gap/unsourced
  • gap/needs-human-replication
  • gap/needs-replication
  • gap/not-checked
  • gap/no-fulltext-access

3 items with this tag.

• Aug 18, 2026

  ftl1

  • gap/not-in-genage
  • gap/long-term-unknown
  • gap/dose-response-unclear
  • gap/no-mechanism

• Aug 18, 2026

  fth1

  • gap/not-in-genage
  • gap/needs-human-replication
  • gap/no-fulltext-access

• Aug 18, 2026

  2026-05-20

  • gap/no-mechanism
  • gap/no-fulltext-access
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/dose-response-unclear
  • gap/not-in-genage
  • gap/unsourced
  • gap/needs-canonical-id
  • gap/needs-peer-review

5 items with this tag.

• Aug 18, 2026

  slc7a11

  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/dose-response-unclear
  • gap/not-populated

• Aug 18, 2026

  nrf2

  • gap/needs-replication
  • gap/needs-human-replication
  • gap/long-term-unknown
  • gap/not-populated
  • gap/contradictory-evidence
  • gap/dose-response-unclear
  • gap/no-fulltext-access

• Aug 18, 2026

  ifnar2

  • gap/needs-replication
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/no-fulltext-access
  • gap/not-populated

• Aug 18, 2026

  cxcr4

  • gap/not-populated
  • gap/needs-replication
  • gap/no-mechanism

• Aug 18, 2026

  beta-arrestin2

  • gap/not-populated
  • gap/needs-replication
  • gap/needs-human-replication
  • gap/no-mechanism
  • gap/contradictory-evidence

7 items with this tag.

• Aug 18, 2026

  tin2

  • gap/needs-canonical-id
  • gap/no-mechanism
  • gap/needs-replication
  • gap/not-queried

• Aug 18, 2026

  trf1

  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/not-tested
  • gap/not-queried
  • gap/no-fulltext-access

• Aug 18, 2026

  sting

  • gap/needs-canonical-id
  • gap/needs-replication
  • gap/unsourced
  • gap/needs-human-replication
  • gap/not-queried
  • gap/long-term-unknown
  • gap/no-fulltext-access

• Aug 18, 2026

  il-1ra

  • gap/no-mechanism
  • gap/needs-replication
  • gap/not-queried
  • gap/needs-canonical-id
  • gap/unsourced
  • gap/no-fulltext-access

• Aug 18, 2026

  growth-hormone-receptor

  • gap/needs-citation
  • gap/needs-replication
  • gap/contradictory-evidence
  • gap/stub
  • gap/no-mechanism
  • gap/needs-human-replication
  • gap/not-queried

• Aug 18, 2026

  chrna7

  • gap/needs-human-replication
  • gap/unsourced
  • gap/contradictory-evidence
  • gap/long-term-unknown
  • gap/needs-stub
  • gap/no-mechanism
  • gap/not-queried

• Aug 18, 2026

  R25

  • gap/no-fulltext-access
  • gap/not-queried
  • gap/unsourced
  • gap/no-uniprot-noncoding-rna
  • gap/needs-citation
  • unsourced
  • gap/needs-replication
  • gap/needs-mechanistic-detail
  • gap/no-mechanism

1 item with this tag.

• Aug 18, 2026

  Non-invasive epidermis sampling for DNA methylation-based prediction of skin cancer phenotypes

  • gap/needs-human-replication
  • gap/needs-replication
  • gap/no-mechanism
  • gap/not-reported

1 item with this tag.

• Aug 18, 2026

  trf1

  • gap/needs-human-replication
  • gap/contradictory-evidence
  • gap/needs-replication
  • gap/not-tested
  • gap/not-queried
  • gap/no-fulltext-access

2 items with this tag.

• Aug 18, 2026

  nefl

  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/needs-human-replication
  • gap/needs-tissue-expression-data
  • gap/no-mechanism
  • gap/not-tested-mr
  • gap/needs-canonical-id

• Aug 18, 2026

  nfl-biomarker

  • gap/needs-canonical-id
  • gap/needs-replication
  • gap/no-fulltext-access
  • gap/no-mechanism
  • gap/unsourced
  • gap/long-term-unknown
  • gap/not-tested-mr
  • stub